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Best American Restaurants in W. University / Med Center

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159 restaurants available nearby

A photo of Drake's Hollywood - Houston restaurant
4.6
Exceptional(173)
Price: Very Expensive
• American • Montrose
Drake's Hollywood in Montrose, Houston, is a haven for steak aficionados, offering an experience that is as authentic as it is exceptional. Known for its “amazing” dry-aged Delmonico steaks, the restaurant consistently receives rave reviews for both its culinary offerings and vibrant ambiance. Diners frequently highlight the “mouth-watering” quality of the steaks, with one reviewer declaring it as “the best steak” they've ever tasted. Each steak is perfectly prepared, capturing the essence of Old Hollywood glamour with every bite. The impeccable service and lively atmosphere only enhance the dining experience, making it a must-visit destination for steak lovers.
A photo of Milton's restaurant
4.7
Exceptional(79)
Price: Expensive
• American • Rice Village
Booked 47 times today
Milton's is a delightful culinary gem nestled in the heart of Rice Village, Houston, offering an exceptional blend of American and Italian-American cuisine that truly stands out. Known for "delicious food and perfect service," Milton's is celebrated for its homemade pastas, like the unforgettable mushroom pasta, and wood-fired meats that offer a comforting yet innovative dining experience. Guests rave about the "outstanding service and food quality," making it a must-visit for those seeking authentic American flavors with a twist. The vibrant atmosphere and impeccable service ensure that every visit is memorable, promising patrons a taste of true American dining excellence.
A photo of Rosie Cannonball restaurant
4.7
Exceptional(42)
Price: Expensive
• American • Montrose
Booked 61 times today
Rosie Cannonball in Montrose, Houston, is a vibrant celebration of authentic Italian cuisine, skillfully prepared with a focus on live fire cooking. The restaurant's wood-burning oven and grill bring out the best in their hand-crafted pastas and wood-fired pizzas, drawing rave reviews for their "perfection" and "top quality." The menu, inspired by fresh, local ingredients, pairs exquisitely with an Italian-centric wine list curated by Master Sommelier June Rodil. Diners consistently praise the "extraordinary" service and "exceptional" food, making it a beloved gem in the heart of Houston. With its lively atmosphere and delectable offerings, Rosie Cannonball promises an unforgettable Italian dining experience.
A photo of Eunice restaurant
4.7
Exceptional(2617)
Price: Moderate
• American • Upper Kirby / Shepherd Corridor
Booked 22 times today
Eunice, nestled in the vibrant Upper Kirby area of Houston, is a seafood lover's paradise, offering a tantalizing menu inspired by the rich flavors of South Louisiana. The restaurant's seafood dishes, such as the "best gumbo I ever had" and the "outstanding oysters," are frequently praised for their authenticity and quality, transporting diners straight to the Gulf Coast. Executive Chef Drake Leonards masterfully infuses European influences with local ingredients, creating a unique culinary experience that keeps guests coming back for more. The warm, inviting atmosphere and exceptional service make Eunice an unforgettable dining destination for seafood enthusiasts.
A photo of Balboa Surf Club restaurant
4.8
Exceptional(60)
Price: Expensive
• American • Galleria / Uptown
Booked 64 times today
Balboa Surf Club in the vibrant Uptown Houston area is a must-visit for seafood lovers. The restaurant is renowned for its exquisitely fresh seafood, with diners raving about the "best seafood I've ever had in Houston!" Guests are consistently impressed by the quality and creativity of the offerings, like the "mind-blowing creative" sushi rolls and the "HUGE crab cake" packed with flavor. The Miso Salmon is frequently highlighted as "some of the best tasting salmon," while the King Crab hand roll is hailed as "the best bite in Houston." Balboa Surf Club promises a culinary experience where freshness and authenticity shine through every dish.
A photo of Clark's Oyster Bar - Houston restaurant
4.8
Exceptional(409)
Price: Expensive
• American • Montrose
Booked 62 times today
Clark's Oyster Bar in Montrose, Houston, is a shining gem of Contemporary American cuisine, delighting diners with its exquisite blend of fresh seafood and classic American dishes. This vibrant restaurant is renowned for its "amazing oysters and seafood," bringing flavors from places like Maine and the Pacific Northwest to the heart of Houston. Diners rave about the "delicious variety of oysters" and the "best cioppino ever," making it a must-visit for seafood aficionados. The light, airy ambiance, complete with a charming outdoor patio, offers a perfect setting to enjoy a "wonderful experience" with "great food and service." Whether you're savoring a classic lobster roll or indulging in a luscious key lime tart, Clark's promises an authentic and memorable Contemporary American dining experience.
A photo of Leo's River Oaks restaurant
4.6
Exceptional(87)
Price: Very Expensive
• American • River Oaks
Booked 36 times today
Leo's River Oaks in Houston is a shining star of Contemporary American cuisine, offering an exquisite dining experience that's hard to match. Guests rave about the "amazing food and cocktails," with standout dishes like the King Salmon and deviled egg trio leaving a lasting impression. The restaurant's elegant decor and live piano music provide a sophisticated atmosphere, perfect for special occasions or a memorable night out. Diners frequently mention the "outstanding service," highlighting the attentive and knowledgeable staff who enhance the dining experience. Leo's River Oaks is truly a "must-try" for anyone seeking exceptional Contemporary American dining in River Oaks.
A photo of Hudson House - River Oaks restaurant
4.7
Exceptional(412)
Price: Moderate
• American • River Oaks
Booked 93 times today
Hudson House - River Oaks is a seafood lover's paradise, bringing the authentic flavors of the East Coast to Houston with a flair for freshness and quality. The oysters, "flown in daily," are a testament to their commitment to providing only the best, and pair perfectly with their renowned "World’s Coldest Martinis." The reviews speak volumes, with diners raving about the "superb" raw oysters and the "best grilled redfish" they've ever had in Houston. The restaurant’s dedication to serving consistently delicious seafood makes it a standout choice for anyone craving an unforgettable seafood dining experience.
A photo of JOEY Uptown restaurant
4.6
Exceptional(98)
Price: Moderate
• American • West Side
Booked 147 times today
JOEY Uptown in Westside, Houston, offers an exceptional dining experience with its Global, International cuisine. With a team of celebrated Executive Chefs, this restaurant delivers a "scrumptious" and "perfectly crafted" menu that has patrons raving about its diverse and flavorful dishes. The open concept dining room and temperature-controlled patio create a lively and inviting atmosphere, accented by art from local talents. Guests consistently praise the "fantastic food, excellent service, and great vibe," making JOEY Uptown a must-visit for anyone seeking a unique and memorable culinary adventure. Whether for a special occasion or a casual night out, this spot is sure to impress.
A photo of Grace's restaurant
4.8
Exceptional(4312)
Price: Expensive
• American • Upper Kirby / Shepherd Corridor
Booked 68 times today
Grace's, nestled in the vibrant Upper Kirby / Shepherd Corridor of Houston, offers an authentic Comfort Food experience that transports diners back to the heartwarming meals of their childhood. Inspired by Johnny Carrabba’s grandmother, Grace Mandola, the restaurant serves up exceptional dishes filled with "the best home style cooking in Houston." Guests frequently rave about iconic comfort dishes, like the "possibly the best chicken fried chicken I've ever eaten," paired with creamy mashed potatoes and jalapeño cream gravy. The charming atmosphere, coupled with outstanding service, creates a cozy haven for diners seeking both nostalgia and culinary excellence.

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See what locals rave about

From verified diners like you
From verified diners like you
  • Mary
    Houston •1 review
    5.0
    Dined 1 day ago
    Took vegan burger off menu. Lettuce wraps weren't as flavorful as normal. Took Donuts off menu.
    More info
    JOEY UptownPrice: Moderate• American• West Side
    4.6
  • DanielVIP
    Houston •40 reviews
    5.0
    Dined 1 day ago
    We enjoyed all aspects of this restaurant. Very intriguing and delicious menu items. The service was great. The music was a bit too loud but you could still carry on conversation. Overall we look forward to going again.
    More info
    Milton'sPrice: Expensive• Italian• Rice Village
    4.7
  • SherrellVIP
    San Francisco Bay Area •13 reviews
    5.0
    Dined 1 day ago
    I’ve been dying to go to Drakes and it did not disappoint. It was a quiet night. The service was top tier. Our waiter, Anthony, was amazing. Had great recommendations! Not a lot of people there, so we missed out on the vibes. But definitely will be back!
    More info
    Drake's Hollywood - HoustonPrice: Very Expensive• American• Montrose
    4.6
  • AzherVIP
    Houston •2 reviews
    5.0
    Dined 3 days ago
    Would have preferred a few more seafood & non pork protein options
    More info
    Rosie CannonballPrice: Expensive• Contemporary American• Montrose
    4.7
  • RachaelVIP
    Houston •12 reviews
    5.0
    Dined 3 days ago
    The exterior leading to the entrance door is stunning. With all the wood detail, you can see the build was thoughtfully planned out. Upon entering you're surrounded by wood detail and live beautiful plants and palms. Our favorite appetizers were the coconut shrimp and fried oysters. Both had so much flavor. We shared the el pescador grouper sandwich with wonderfully crispy fries and tasty sauces to accompany them. We finished with a dessert, the quattro leches, absolutely amazing! And we were given a free dessert, for our wait on the entree, of chocolate pie. This slice of pie was heaven! It was so creamy and included the flavor (and smell) of espresso! A must have! The bar area was nice and next time we will sit at the bar and view sports on the TV.
    More info
    Balboa Surf ClubPrice: Expensive• American• Galleria / Uptown
    4.8

Discover best American restaurants in W. University / Med Center

Explore the vibrant American dining scene in Houston's W. University / Med Center area, where culinary excellence meets diversity. This neighborhood is renowned for its American cuisine, offering a range of restaurants that exemplify the rich gastronomic culture with innovative dishes and high-quality ingredients. Each establishment in this locale is celebrated for its superb service, unique ambiance, and commitment to using locally-sourced produce, reflecting the authenticity and regional flavors of American cooking. Diners can expect a delightful experience, with menus that cater to all tastes, from traditional comfort foods to modern interpretations that push culinary boundaries. The dining scene here is not just about food; it’s about creating memorable experiences, where every meal is served with a touch of sophistication and a deep appreciation for culinary arts. Whether you are seeking a casual dining experience or a sophisticated evening out, the American restaurants in Houston's W. University / Med Center area promise to satisfy your cravings and leave you eager for your next visit.

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