Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Fusion Restaurants in Medical Center

Price
Regions
Areas
Dining Options
Seating options
Accessibility

5 restaurants available nearby

A photo of Paladar Fusion Mexico Cuba restaurant
1. Paladar Fusion Mexico Cuba
4.8
Exceptional(23)
Price: Moderate
• Fusion • Alamo Heights
Booked 1 time today
Experience the vibrant flavors of Mexico at Paladar Fusion Mexico Cuba, nestled in the charming Alamo Heights neighborhood of San Antonio. This unique eatery expertly blends the bold and spicy essence of Mexican cuisine with the colorful vibrancy of Cuban dishes, creating a culinary fusion that delights and surprises. Diners rave about the "incredible" Tostones Rellenos and the "insane" shrimp tacos with melted Oaxaca cheese, highlighting the restaurant's commitment to authenticity and quality. As one enthused diner puts it, Paladar is a "must try!" with dishes that are "perfectly flavored" and a cozy yet elegant tropical ambiance that makes every meal feel special. Whether it's the attentive service or the innovative menu, Paladar Fusion Mexico Cuba stands out as a beacon of excellent Mexican cuisine in San Antonio.
A photo of Tokyo Cowboy restaurant
2. Tokyo Cowboy
4.5
Awesome(212)
Price: Expensive
• Fusion • Downtown
Booked 17 times today
Tokyo Cowboy in Downtown San Antonio is a must-visit for lovers of Tapas and Small Plates with a unique twist. This Asian-inspired diner seamlessly blends Japanese and Texan flavors, creating an unforgettable culinary experience. Patrons rave about the brisket egg rolls and hot chicken dumplings, describing them as "phenomenal" and a "game changer." The atmosphere is consistently praised as "beautiful" and "delightful," making it an ideal spot for both casual and special occasions. With its creative cocktails and exceptional service, Tokyo Cowboy stands out as a top destination for authentic and innovative small plates. Experience why diners say, "Get all of the things!!" and ensure you don't miss out on this culinary gem in the heart of San Antonio.
A photo of MASH'D San Antonio – The Original Culinary Bastards restaurant
3. MASH'D San Antonio – The Original Culinary Bastards
4.6
Exceptional(1153)
Price: Moderate
• Fusion • Stone Oak
Booked 6 times today
MASH'D San Antonio – The Original Culinary Bastards in Stone Oak offers a standout Contemporary American dining experience, celebrated for its innovative and memorable flavors. Patrons rave about the "fantastic blackberry mimosas" and "amazing chicken and biscuits," highlighting the freshness and quality of the cuisine. The restaurant's vibrant and welcoming atmosphere is matched by exceptional service, with reviews praising staff like Savanah for being "attentive, friendly, and knowledgeable." Whether it's the unique avocado toast pizza or the perfectly seasoned meatloaf, every dish is crafted to perfection, making MASH'D a culinary gem in San Antonio's dining scene.
A photo of Nicosi restaurant
4. Nicosi
4.9
Exceptional(45)
Price: Very Expensive
• Fusion • Downtown
Booked 5 times today
Nicosi, nestled in Downtown San Antonio, stands as a beacon of Fusion / Eclectic cuisine, expertly intertwining acid, sweet, bitter, and savory to redefine dessert experiences. With only 20 seats encircling the vibrant kitchen, the intimate setting allows for a direct dialogue with the chefs, enhancing the educational journey through each dish. Praised for its "unique and wonderful experience" and "mind-boggling" culinary experimentation, Nicosi crafts a multi-course dessert tasting that is as much a spectacle as it is a dining experience. Guests are treated to innovative pairings and a theatrical presentation, creating unforgettable moments. As one review exclaims, "Forget everything you thought you knew about dessert," Nicosi is not just a meal but an "extraordinary experience" that challenges and delights the palate in the most unexpected ways.
A photo of Ácenar restaurant
5. Ácenar
4.5
Awesome(2597)
Price: Moderate
• Fusion • Downtown
Booked 13 times today
Ácenar, nestled in the vibrant heart of Downtown San Antonio, offers a unique and invigorating fusion of Texas regional and Mexican cuisines. This contemporary culinary gem, helmed by the renowned restaurateurs Lisa Wong and Pete Selig, presents an eclectic menu that dazzles with its bold Latin-infused flavors. Executive Chef Richard Sánchez masterfully crafts dishes like the seafood enchiladas and San Antonio style enchiladas, which are consistently lauded for their authenticity and innovation. Diners rave about the "amazing" Tres Leches cake and the "incredible" mole enchiladas, highlighting the restaurant's commitment to quality and creativity. With its prime river walk location and a modern, stylish setting, Ácenar is a standout destination for those seeking a sublime fusion dining experience.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you

Explore OpenTable

Discover
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Our sites
Businesses
  • Delight more diners
  • Restaurant Blog
Join us on
  • Privacy Policy
  • Terms of Use
  • Impressum
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable International Ltd. Alphabeta Building, 14-18 Finsbury Square, London EC2A 1AH - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo