Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. Dallas - Fort Worth

Best Southwest American Restaurants in Medical District

Price
Regions
Areas
Top Rated
Dining Options
Seating options
Award-winning
Accessibility

195 restaurants available nearby

A photo of Maple Landing restaurant
1. Maple Landing
4.6
Exceptional(76)
Price: Moderate
• Mexican • Medical District
Booked 2 times today
Maple Landing in Dallas's Medical District is a must-visit for anyone craving authentic and high-quality American cuisine. Nestled near Love Field, this "wanna be" dive-bar delights with its aviation-themed ambiance and a mouth-watering menu that boasts everything from brisket to burgers. Patrons rave about the unique offerings like the "Brisket Poutine" and the "Pork Belly Pastor Tacos," describing them as "amazing" and a "must-try." The culinary craftsmanship is evident, with reviews highlighting the "smoked pork chop" and the "chili cheeseburger of my dreams." The laid-back atmosphere is consistently praised, making it a favorite for both locals and travelers. "Great bourbon selection and the brisket was unexpectedly in line with the best in Dallas," one review exclaims, emphasizing Maple Landing's commitment to quality and flavor that keeps guests returning for more.
A photo of Hudson House - Lovers Lane restaurant
2. Hudson House - Lovers Lane
4.8
Exceptional(726)
Price: Expensive
• Mexican • Park Cities
Booked 81 times today
At Hudson House - Lovers Lane in Park Cities, Dallas, seafood lovers are in for a treat, especially with the oysters that are flown in daily, ensuring freshness and quality that’s hard to match. The restaurant's dedication to authenticity is evident, as one diner raved, "Every time we’ve ordered oysters they’re consistently fresh and the variety they offer is unmatched to anywhere else." Not only are the seafood offerings top-notch, but the atmosphere and service complement the dining experience beautifully, making every visit memorable. Whether it's the perfectly tender shrimp cocktail or the fresh oysters, Hudson House stands out as a premier destination for exceptional seafood cuisine.
A photo of The Mexican restaurant
3. The Mexican
4.7
Exceptional(1034)
Price: Very Expensive
• Mexican • Design District
Booked 83 times today
Nestled in the vibrant Design District of Dallas, The Mexican stands as a beacon of authentic Mexican cuisine. This restaurant is celebrated for its dedication to heritage recipes and an innovative approach that brings bold flavors to the forefront using the finest ingredients. Guests consistently rave about their experiences, with one noting, "The food was incredible, and the service was outstanding" and another declaring the Cuatro Leches cake "the best dessert I have ever had in my life!" Whether it's the exquisite lobster tacos or the meticulously crafted margaritas, The Mexican delivers an unforgettable dining experience that is both authentic and enchanting. Perfect for any occasion, it's a must-visit for anyone craving a taste of true Mexican culinary artistry in Dallas.
A photo of Drake's Hollywood - Dallas restaurant
4. Drake's Hollywood - Dallas
4.7
Exceptional(470)
Price: Very Expensive
• Mexican • Park Cities
Booked 51 times today
An Old Hollywood party - dry-aged steaks & cold martinis*Drake's Hollywood accepts reservations for parties of 7 or less. For parties of 8+ please contact events@drakeshollywood.com. Happy Hour is available weekdays 4pm to 6pm in the bar. For more information, visit our website.
A photo of Perry's Steakhouse & Grille - Park District restaurant
5. Perry's Steakhouse & Grille - Park District
4.8
Exceptional(9576)
Price: Expensive
• Mexican • Uptown
Booked 108 times today
Perry's Steakhouse & Grille - Park District in Uptown Dallas is renowned for more than just its steaks; it’s a seafood haven that promises an extraordinary dining experience. Set against a backdrop of stunning views of Klyde Warren Park and Downtown Dallas, the restaurant offers a menu that triumphs in both quality and authenticity of its seafood offerings. Diners rave about the consistency and excellence of the dishes, with one guest exclaiming, "The service and seafood here are amazing!" Whether it's for a special occasion or a delightful dinner, Perry’s seafood cuisine, including their crab-stuffed mushrooms and lobster bisque, is prepared to perfection, making each visit memorable. Celebrate your next outing here for a taste of some of the best seafood in Dallas.
A photo of Sister restaurant
6. Sister
4.9
Exceptional(86)
Price: Expensive
• Mexican • Park Cities
Booked 65 times today
Nestled in the historic heart of Park Cities, Dallas, Sister restaurant stands out as a beacon of American culinary excellence. Housed in the iconic space formerly known as The Grape, Sister offers a delightful twist on American cuisine with a touch of Mediterranean influence, creating a unique dining experience that's both familiar and innovative. The restaurant's ambiance, described as "quirky and playful," perfectly complements its high-quality, wood-fired meats and freshly made pastas. Glowing reviews consistently praise Sister, with one diner raving, "Every dish was absolutely amazing and surprising" and another celebrating the "phenomenal service" that made their dining experience unforgettable. Sister not only continues the legacy of its beloved predecessor but enhances it, making it a must-visit destination for anyone seeking the best in American dining in Dallas.
A photo of The Henry - Dallas restaurant
7. The Henry - Dallas
4.7
Exceptional(2889)
Price: Moderate
• Mexican • Dallas-Ft. Worth (DFW) Corridor
Booked 150 times today
At The Henry in the bustling Dallas-Ft. Worth Corridor, diners are treated to a quintessentially American dining experience that's both heartwarming and delightful. Known for its "craveable eats and downright delicious cocktails," The Henry epitomizes American cuisine with a menu that celebrates classic flavors with a modern twist. Guests rave about the "delicious food and excellent service," highlighting signature dishes like the Korean Prime Skirt Steak and Short Rib Potstickers as standouts. The inviting ambience, combined with a staff that "anticipates needs," makes every meal memorable. Whether it's a business lunch or a leisurely brunch, The Henry consistently delivers an authentic, high-quality American dining adventure, making it a beloved spot among locals and visitors alike.
A photo of Mister Charles restaurant
8. Mister Charles
4.8
Exceptional(133)
Price: Expensive
• Mexican • Knox / Henderson
Booked 78 times today
Mister Charles in Dallas' iconic Knox / Henderson neighborhood is a jewel of Contemporary American cuisine. Housed in the historic Highland Park Soda Fountain Building, this restaurant offers a thrilling blend of French and Italian influences with a modern American twist. Patrons rave about the "out-of-this-world" food and "phenomenal experience," highlighting dishes like the unique uni carbonara and the exquisite wagyu short rib Wellington. The ambiance, described as having "soaring 38-ft. ceilings" and "opulent design," complements the culinary artistry perfectly. With glowing reviews declaring it "one of the best" in Dallas, Mister Charles continues to raise the bar for fine dining in the city. Whether celebrating a special occasion or seeking an exceptional meal, it promises an unforgettable experience.
A photo of Nuri Steakhouse - Uptown restaurant
9. Nuri Steakhouse - Uptown
4.6
Exceptional(191)
Price: Very Expensive
• Mexican • Uptown
Booked 55 times today
Discover the epitome of Steakhouse cuisine at Nuri Steakhouse in Uptown, Dallas, where Chef Minji Kim's Michelin-recognized expertise meets the vibrant culinary traditions of Asia, New Orleans, and the South. Patrons rave about the exceptional quality of the steaks, noting the "Perfectly cooked beautiful steaks" and praising their "great marbling" and sublime taste even without sauces. The restaurant's stunning ambiance, combined with the attentive, knowledgeable service, makes every dining experience unforgettable. As one guest put it, the filet was the "BEST I've ever eaten....ridiculously good!" At Nuri, expect not just a meal, but a "luxurious, unforgettable dining journey" celebrated by all who visit.
A photo of The Charles restaurant
10. The Charles
4.8
Exceptional(91)
Price: Very Expensive
• Mexican • West Dallas
Booked 48 times today
Located in the vibrant West Dallas neighborhood, The Charles is a beacon of American cuisine, celebrated for its innovative twist on classic flavors. Patrons rave about its "top tier food, drink, and experience," with every dish crafted to perfection, from the homemade pastas to the exquisitely prepared Berkshire Porkchop. The restaurant's commitment to excellence is echoed in its reviews, as diners consistently highlight the "exceptional service" and "attention to detail." The Charles is not just a meal; it’s a culinary adventure, with a lively ambience that complements its creative cuisine. As one reviewer puts it, it's "legitimately one of the best culinary experiences I’ve had," making The Charles a must-visit destination for anyone seeking the pinnacle of American dining in Dallas.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you

Explore OpenTable

Discover
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Our sites
Businesses
  • Delight more diners
  • Restaurant Blog
Join us on
  • Privacy Policy
  • Terms of Use
  • Impressum
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable International Ltd. Alphabeta Building, 14-18 Finsbury Square, London EC2A 1AH - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo