Best Southwest American Restaurants in Greenville

25 restaurants available nearby

1. Soby's

4.7

Exceptional(9067)

Price: Moderate

• Mexican • Greenville

Booked 45 times today

Located in the heart of downtown Greenville, Soby's offers an unforgettable Southern dining experience with its eclectic blend of contemporary continental cuisine and traditional Southern ingredients. Nestled in a beautifully renovated 1800s cotton mill, the restaurant exudes charm and warmth. Reviewers rave about classic Southern dishes like "fried green tomatoes" and "she crab soup," which are consistently praised for their authentic flavors. The wine list, a regular award-winner by Wine Spectator Magazine, perfectly complements the culinary delights. Guests commend Soby's for its "impeccable service" and "outstanding food," making it a must-visit destination for anyone craving genuine Southern cuisine.

2. CAMP

4.8

Exceptional(460)

Price: Expensive

• Mexican • Greenville

Booked 62 times today

CAMP/kamp/ verb: To relax, chill, unwind, savor, reflect, enjoy, breatheStep through the doors of CAMP and you know you’re in good company. Here is a gathering place that captures the essence of downtown Greenville perfectly—cool, comfortable, lively—with food that is insanely delicious and flavorful.The whimsical, comfort food menu with its touch of global flair is crafted using only the freshest, seasonal ingredients sourced directly from local farms. Refreshing cocktails, a curated wine list, and a selection of regional beers pair perfectly to ensure a remarkable dining experience. Come unwind, chill with friends, and savor the moment at CAMP.

3. Juniper

4.4

Awesome(502)

Price: Expensive

• Mexican • Greenville

Booked 71 times today

Step away from the downtown bustle to experience Juniper, Greenville's only urban gin bar, situated atop the AC Hotel. From the moment you enter Juniper, prepare to be enchanted by its immersive rooftop garden and breathtaking views of Main Street and the Blue Ridge Mountains.Full Dinner Menu: Available Wednesday & Thursday from 5 pm to 10 pm | Friday & Saturday from 5 pm to 11 pm.Attire: We encourage SMART CASUAL dress at Juniper. Please refrain from beachwear, active/athletic attire, and work uniforms, with exceptions for government, law enforcement, healthcare, or military personnel. Men should avoid sleeveless/tank tops.Identification: Remember to bring a valid physical I.D. (US Issued Driver's License/ID or Passport are accepted).Underage Guests: Must be accompanied by an adult aged 21 or older. After 10pm: 21 or older only.Gratuity: A 20% gratuity will be automatically added to parties of 8 or more.Cake Fee: $35 fee applies for cake/cupcakes.Corkage Fee: $45/bottle

A photo of Tupelo Honey - Greenville restaurant

4. Tupelo Honey - Greenville

4.7

Exceptional(3583)

Price: Moderate

• Mexican • Greenville

Booked 77 times today

Tupelo Honey - Greenville is a delightful celebration of American Southern cuisine, rooted in the rich traditions of the Carolina Mountains. Known for its "scratch-made" dishes, the restaurant guarantees a genuine taste of Southern hospitality with every meal. Diners rave about the "delicious" and "authentic" flavors, with standout dishes like fried green tomatoes and chicken and waffles that keep guests returning. The atmosphere is described as "cozy" and perfect for lingering conversations, while the service is consistently praised as "phenomenal." Whether it's brunch, lunch, or supper, Tupelo Honey offers a warm and welcoming experience that embodies the heart of American cuisine.

5. Nose Dive

4.6

Exceptional(1925)

Price: Moderate

• Mexican • Greenville

Booked 24 times today

Nestled in the vibrant heart of Downtown Greenville, Nose Dive stands out as a prime destination for authentic Gastro Pub cuisine. This delightful eatery, a gem from the renowned Table 301 Restaurant Group, offers an eclectic menu that perfectly balances comfort foods with traditional pub fare. Diners rave about the "best burger" and "outstanding" fish and chips, highlighting the restaurant's commitment to quality ingredients and flavorful dishes. The inviting atmosphere, enhanced by the charming outdoor seating, is frequently praised for its "great ambiance." Nose Dive's attentive service and handcrafted selection of beers and wines make it a must-visit spot for both locals and visitors alike.

6. Larkin's

4.3

Awesome(5198)

Price: Expensive

• Mexican • Greenville

Booked 50 times today

Larkin's in downtown Greenville is a top-notch destination for authentic American cuisine that truly shines. Located at the heart of the vibrant Camperdown Plaza, it offers a contemporary setting that honors Greenville's rich history. Diners rave about the "exceptional" food, praising the expertly prepared steaks, seafood, and diverse menu items like the "best ever" French onion soup and truffle fries. The Wine Spectator Award-winning wine list and carefully curated craft beers complement the upscale dining experience. With "impeccable service" and multiple dining atmospheres, including outdoor seating, Larkin's is perfect for any occasion, from pre-show dinners to romantic dates.

A photo of Draper Purveying Company restaurant

7. Draper Purveying Company

4.5

Awesome(46)

Price: Moderate

• Mexican • Greenville

Booked 15 times today

Draper Purveying Company in downtown Greenville offers a vibrant and inviting dining experience with its authentic Contemporary American cuisine. Under the expert guidance of Executive Chef Patrick Phillips, the menu shines with innovative takes on comfort food, such as "crispy confit chicken wings" and "coffee-rubbed tenderloin," that delight the senses. Diners rave about the "wonderful dining experience," highlighting the "amazing food" and "excellent service." The restaurant's atmosphere is lively and welcoming, making it perfect for any occasion. With "delicious food" and a thoughtfully curated bar menu, Draper Purveying Company is a must-visit destination for those seeking exceptional Contemporary American fare.

8. Oak & Honey

4.6

Exceptional(136)

Price: Expensive

• Mexican • Greenville

Booked 5 times today

Oak & Honey stands out as a beacon of Mediterranean excellence in the heart of Greenville. Diners rave about the "absolutely amazing" and "delicious" dishes that showcase the authentic Mediterranean flavors, while the ambiance is described as both "comfortable" and "inviting." This restaurant’s commitment to quality is evident in its "made-from-scratch seasonal fare," which leaves guests eager to return for more. The standout calamari and brussel sprouts are a favorite, epitomizing the fresh, vibrant ingredients of Mediterranean cuisine. With a stellar staff known for their "top level service," Oak & Honey promises an unforgettable Mediterranean dining experience.

A photo of Sassafras Southern Bistro restaurant

9. Sassafras Southern Bistro

4.9

Exceptional(3404)

Price: Moderate

• Mexican • Greenville

Booked 47 times today

Sassafras Southern Bistro, situated in the bustling heart of downtown Greenville, South Carolina, is a gem of American cuisine with an irresistible Southern flair. Known for its eclectic menu, this restaurant expertly crafts dishes like "the raved-about shrimp and grits" and the delectable pecan-crusted rainbow trout, enticing diners from near and far. Guests frequently praise the "lively, friendly atmosphere," with service that is consistently "top-notch." The full bar, boasting local beers and an extensive wine selection, complements the culinary experience. "A truly special place," Sassafras Southern Bistro is a must-visit for anyone seeking authentic American flavors with a Southern twist.

A photo of Nic & Norman's - Greenville restaurant

10. Nic & Norman's - Greenville

4.5

Awesome(187)

Price: Moderate

• Mexican • Greenville

Booked 34 times today

Nic & Norman's in Greenville offers an exceptional Comfort Food experience that has diners raving about its "amazing food and drinks" and "deliciously prepared" dishes. The restaurant's Southern-inspired menu, featuring gourmet burgers, flatbread pizzas, and brunch options, is crafted with fresh, locally-sourced ingredients, ensuring each meal is both innovative and comforting. With standout dishes like the Coca-Cola marinated pork shank and Buffalo chicken flatbread, guests are treated to flavors that feel like "mom’s home cooking." The cozy, speakeasy vibe and attentive service create a welcoming atmosphere, making Nic & Norman's a must-visit for Comfort Food enthusiasts seeking quality and authenticity.

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

Explore OpenTable

Greenville

Mexican

Best Southwest American Restaurants in Greenville

Price

Regions

Areas

Top Rated

Dining Options

Seating options

Accessibility

25 restaurants available nearby

1. Soby's

2. CAMP

3. Juniper

4. Tupelo Honey - Greenville

5. Nose Dive

6. Larkin's

7. Draper Purveying Company

8. Oak & Honey

9. Sassafras Southern Bistro

10. Nic & Norman's - Greenville

Explore OpenTable