4 Best Regional Mexican Restaurants In La Mesa

4 restaurants available nearby

A photo of Mario's De La Mesa Restaurant restaurant

1. Mario's De La Mesa Restaurant

4.5

Awesome(3)

Price: Moderate

• Regional mexican • La Mesa

Booked 1 time today

Experience the heart of Sonora and Sinaloa at Mario's De La Mesa Restaurant, where every dish tells a story of tradition and culinary mastery. Nestled in the vibrant neighborhood of La Mesa, this family-owned gem stands out for its commitment to authenticity and freshness. Patrons rave about the "amazing pico de gallo" and "perfectly cooked shrimp," highlighting the careful attention to quality ingredients and homemade recipes. From the tantalizing machaca and eggs to the creamy jalapeño shrimp, every meal is a fiesta of flavors. As one customer put it, "If I could, I would give this place more than 5 stars. This would be my last meal if I got the death sentence." Mario's is not just a meal; it’s a memorable dining experience that keeps locals and newcomers alike coming back for more. Join us at Mario's for a taste of true Regional Mexican cuisine right here in La Mesa.

A photo of Blanco Cocina + Cantina – Fashion Valley restaurant

2. Blanco Cocina + Cantina – Fashion Valley

4.7

Exceptional(559)

Price: Moderate

• Regional mexican • Mission Valley

Booked 5 times today

Blanco Cocina + Cantina in Mission Valley, San Diego is a vibrant oasis for cocktail lovers seeking a blend of creativity and tradition. Known for its exceptional Cocktail Bar, Blanco transforms every visit into a mini-vacation with its delightful concoctions. Guests rave about the "spicy skinny margaritas" and the "mango margarita," which is described as "refreshing" with a "smoky salt rim" that adds a unique twist. The atmosphere is consistently praised, with diners highlighting the upbeat and welcoming vibe perfect for "a great date night spot" or a "fun gathering with friends." Blanco's ability to merge a lively environment with meticulously crafted cocktails ensures an unforgettable experience for all its visitors.

A photo of Ortega's A Mexican Bistro restaurant

3. Ortega's A Mexican Bistro

4.6

Exceptional(1016)

Price: Moderate

• Regional mexican • Hillcrest

Booked 1 time today

Ortega's A Mexican Bistro, nestled in the vibrant neighborhood of Hillcrest, San Diego, offers a culinary journey to Puerto Nuevo with its authentic Mexican and Southwestern flavors. Diners rave about the Baja style lobster and table side guacamole, calling it a "delicious" and "authentic" experience. The restaurant's festive design and Baja California-inspired menu, including dishes like Banana Crusted Huachinango and Chicken Mole, consistently impress guests. Reviews highlight the "warm and inviting" atmosphere and "friendly and attentive" staff, with one customer exclaiming, "The lobster meal, handmade guacamole, and margaritas are to die for!" Ortega’s stands out as a beloved spot for both locals and visitors, making it a must-visit for anyone craving genuine Mexican cuisine in San Diego.

4. Blind Burro

4.6

Exceptional(672)

Price: Moderate

• Regional mexican • Downtown / Gaslamp

Booked 1 time today

At The Blind Burro in Downtown San Diego, the spirit and flavors of contemporary Mexican cuisine come alive. Nestled in the vibrant East Village, this restaurant stands out for its fresh, coastal Baja-inspired dishes, which guests adore for their authenticity and creativity. Praised for its exceptional service and lively atmosphere, The Blind Burro offers an array of standout dishes, from sizzling surf & turf tacos to the beloved carne asada chimichangas, described by a patron as "phenomenal." Another diner raved, "The best chips and variety of salsas. Delicious drinks such as the sangria and Margarita on the rocks. Highly recommend the lobster tacos. To die for!" It's clear why this spot is a local favorite, perfect for a pre-game meal or a casual meetup, making every visit a delightful culinary adventure.

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

Best Regional Mexican Restaurants in La Mesa

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4 restaurants available nearby

1. Mario's De La Mesa Restaurant

2. Blanco Cocina + Cantina – Fashion Valley

3. Ortega's A Mexican Bistro

4. Blind Burro

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