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Best Southern American Restaurants in Cow Hollow

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140 restaurants available nearby

A photo of Perry's Union Street restaurant
1. Perry's Union Street
4.7
Exceptional(718)
Price: Moderate
• Southern american • Marina / Cow Hollow / Presidio
Booked 21 times today
Perry's Union Street is a beloved San Francisco institution that has mastered the art of Contemporary American cuisine. Known for its "great food and drinks," Perry's offers a menu filled with American classics, from succulent steaks to fresh grilled fish, all served in generous portions. Diners rave about the "exceptional service" and the inviting, lively atmosphere that feels like a neighborhood gathering where "everyone knows your name." With its legacy of over 50 years, Perry's continues to be a go-to spot for locals and visitors alike, promising a timeless dining experience that is both "delicious" and "reasonably priced."
A photo of 6 Tables restaurant
2. 6 Tables
4.6
Exceptional(24)
Price: Moderate
• Southern american • Cow Hollow
Booked 8 times today
A vibrant restaurant offers a unique dining experience by showcasing all day breakfast and brunch dishes inspired by six different world cuisines. Helmed by the creative team behind Okaeri Japanese Bistro and Tadaima, the menu promises something special for every palate. The restaurant also boasts an array of distinctive coffee drinks, craft cocktails, and an impressive selection of wines and beers.
A photo of Palm House restaurant
3. Palm House
4.7
Exceptional(559)
Price: Moderate
• Southern american • Marina / Cow Hollow / Presidio
Booked 6 times today
Hi Friends, We have gone to a full QR Code ordering system but don't be afraid, our team is available to walk you through any questions you may have! We understand that planning is overrated and spontaneity is the spice of life! That's why we always keep availability for walk-ins of groups of 2 or more. Simply walk in and our friendly team will be happy to accommodate you at the door. We now take limited reservations for groups of 2 or more. Please note that while reservations provide a guaranteed table, we strive to accommodate walk-ins as much as possible. Big groups, no problem! However, during peak hours, there might be a short wait time for walk-in groups. Grab a maitai at the bar or play a game of pool while you wait - and hey, you might even meet someone new. Thank you for reserving with us at Palm House!
A photo of Perry's - Embarcadero restaurant
4. Perry's - Embarcadero
4.7
Exceptional(2367)
Price: Moderate
• Southern american • Financial District / Embarcadero
Booked 19 times today
Perry’s - Embarcadero is a beacon of exceptional Contemporary American cuisine, perfectly nestled in San Francisco's vibrant Financial District. With its unparalleled views of the Bay Bridge, this restaurant offers more than just a meal — it's an experience. Diners rave about the "fantastic menu" and "delicious food," highlighting dishes like the petrale sole and clam chowder as standout choices. Known for its warm, personable service, Perry’s is a "go-to place" for locals and visitors alike, whether it's for a casual lunch or a celebratory dinner. The blend of classic American flavors with innovative twists ensures a dining experience that is both comforting and fresh.
A photo of The Brixton restaurant
5. The Brixton
4.3
Awesome(524)
Price: Expensive
• Southern american • Marina / Cow Hollow / Presidio
Booked 3 times today
The Brixton, located in San Francisco's vibrant Marina district, offers an exceptional Contemporary American dining experience that stands out with its innovative and diverse menu curated by renowned Chef Joey Altman. This modern gastropub delights patrons with dishes like the "spicy crispy tuna" and "Chilean sea bass," both praised as "absolutely to die for." The Brixton's ambiance is "gorgeous and upscale," making it a perfect spot for both casual and upscale dining. Guests rave about the "great atmosphere," "friendly service," and a happy hour that's "well worth it." It's a must-visit for those seeking authentic Contemporary American cuisine.
A photo of Trinity restaurant
6. Trinity
4.0
Excellent(6)
Price: Moderate
• Southern american • Cow Hollow
Experience the best of both worlds at Trinity in Cow Hollow. Indulge in Irish-American fusion, where traditional Irish delicacies meet beloved American classics. Each dish is meticulously crafted to delight your taste buds and elevate your dining experience. Join us on Union Street and explore a tantalizing menu that perfectly blends the rich flavors of Ireland with the comforting favorites of American cuisine.
A photo of House of Prime Rib restaurant
7. House of Prime Rib
4.8
Exceptional(16010)
Price: Very Expensive
• Southern american • Civic Center / Hayes Valley / Van Ness
Booked 191 times today
House of Prime Rib in San Francisco is a beacon of authentic American cuisine, renowned for its "iconic" status and exceptional prime rib. With 62 years of unwavering dedication, it’s no surprise that this establishment garners glowing praise from loyal patrons who rave about its "festive" atmosphere and "superb" service. Guests continually highlight the "delicious" prime rib, which is described as "massive" and "perfectly cooked," making every visit a memorable experience. The lively ambiance and the meticulous attention from the staff ensure that every meal feels like a special occasion. Truly, House of Prime Rib offers a quintessential American dining experience.
A photo of Harris' restaurant
8. Harris'
4.8
Exceptional(5598)
Price: Very Expensive
• Southern american • Russian Hill
Booked 49 times today
Harris' in Russian Hill, San Francisco, is a beacon of American culinary excellence, offering a classic steakhouse experience that is second to none. Known for its "superb dining experience," Harris' specializes in dry-aged, mid-western beef, offering steaks that are "cooked to perfection" and "the best steaks ever!" Patrons rave about the impeccable service and the “wonderful holiday setting with exceptional service.” It's more than just a meal; it's an invitation to savor authentic American cuisine in an atmosphere enriched with live jazz. Harris' consistently delivers an elegant dining experience, making it a must-visit for steak enthusiasts and American cuisine lovers alike.
A photo of Original Joe's - San Francisco restaurant
9. Original Joe's - San Francisco
4.7
Exceptional(4299)
Price: Moderate
• Southern american • North Beach
Booked 136 times today
Original Joe's in North Beach, San Francisco, is a beacon of authentic American cuisine blended with rich Italian-American flavors. As a culinary institution for over 80 years, Original Joe’s offers a unique dining experience with its signature red leather booths and legendary smooth cocktails. Reviewers rave about its "fantastic drinks" and "great food," highlighting dishes like the Veal Marsala and house-made ravioli. The ambiance is described as "festive and friendly," making it perfect for any occasion. Whether you're a local or a tourist, Original Joe's promises a classic American experience that "never disappoints," truly making it a San Francisco landmark.
A photo of The Progress restaurant
10. The Progress
4.8
Exceptional(2527)
Price: Very Expensive
• Southern american • Western Addition
The Progress in Western Addition, San Francisco, offers a truly remarkable Californian dining experience. Celebrated for its "innovative menu" and "delicious flavors," this restaurant uses entirely local ingredients to craft dishes that highlight the essence of Californian cuisine. Guests rave about the duck, described as a "must-try" and "100% juicy and tender," alongside other inventive dishes like the seaweed noodles and Tierra vegetables masa dumplings. The ambiance is "casual and playful," providing the perfect setting for what many reviewers describe as "the best meal in SF." With excellent service and a creative menu, The Progress is an unmissable culinary gem.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Melody
    San Francisco Bay Area •5 reviews
    5.0
    Dined 3 days ago
    It was the perfect date night spot. I came here solo and enjoyed a feast! The staffs are super attentive and service was beyond expectations. Food was very unique for a southern charm and taste great!
    More info
    PreludePrice: Expensive• Californian• Financial District / Embarcadero
    •
    4.7
  • JeannieVIP
    San Francisco Bay Area •31 reviews
    5.0
    Dined 5 days ago
    This place is full of heartwarming flavors of Southern comfort food. Definitely a neighborhood gem. Every bite feels like a warm hug from home. The menu was full of classic favorites and the service team was friendly and attentive. They checked in with us often, perhaps a bit too often however, their dedication was not disappointing. The atmosphere strikes the perfect balance of kindness and wit, offering a welcoming space for laughter and great conversation. It’s the kind of place where delicious food meets delightful company, making our visit a memorable one. The corn muffins are out of this world, adding butter and honey. The fried chicken was crispy, moist and flavorful on the inside. BBQ pull pork sandwich was perfect, tender, tangy and sweet. Side dishes were macaroni & cheese and collard greens, prepared just right. Parking can be a challenge, street and meter parking. They accept reservations through OpenTable.
    More info
    Hard Knox Cafe on Clement StreetPrice: Moderate• Regional American (Southern)• Richmond District
    •
    4.9
  • Angel
    San Francisco Bay Area •1 review
    5.0
    Dined on 2 Mar 2025
    It was my first time there. Great intimate setting. Everyone was super friendly. My only suggestion would be. Because of the name biscuits and blues… The biscuit other than the entertainment needs to be the star!
    More info
    Biscuits and BluesPrice: Expensive• Regional American (Southern)• Downtown / Union Square
    •
    4.7

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